(PDF) Stem Cell and Gene Therapy for Cardiovascular Disease by Perin

This is the PDF eBook version for Stem Cell and Gene Therapy for Cardiovascular Disease by Emerson C. Perin, Leslie W. Miller, Doris Taylor, James T. Willerson

Table of Contents

1. Introduction and Overview of Stem Cells
2. Mechanistic Insights from Pathologic Perspective
3. Large Animal Models to Study Stem Cell Therapy
4. Evolution of understanding of the mechanisms of repair
5. Impact of Age on Stem Cell Function
6. Bone Marrow Mononuclear Cells
7. Chronic Limb Ischemia
8. Chronic/Refractory Angina
9. Acute Myocardial Infarction
A. European Experience
B. US Experience
10. Chronic Ischemic Heart Failure
11. Adipose Tissue
12. Overview of MSCs
13. Allogeneic vs Autologous Source: Comparative Effects
14. Use of MSCs for AMI
15. Combined Cell Strategies
16. Heart Failure
17. C-Kit cells
18. Cardiospheres
19. Umbilical Cord, Placenta, Endometrium
20. Genetic Engineering of Fibroblasts to Cardiomyocytes
21. Transformation to inducible Pleuripotent Stem Cells
22. Transformation to MAPC’s
23. Transcoronary and Endocardial
24. Retrograde and Epicardial
25. Epicardial Patch
26. Matrix Scaffolds
27. Matrix plus cells
28. Biomaterial: Alginate
29. Organogenesis
30. Pre-clinical Identification of target genes
31. SERCA-2a gene for recovery of inotropic function
32. SDF-1 Gene for Heart Failure Non-Inotropic Mechanisms
33. Gene Therapy for Angiogenesis: Chronic Limb Ischemia
34. Stem Cells Target Gene Transfected Stem Cells
35. CCTRN: Past, Present, and Vision for the Future
36. Signature of Responders-lessons from Bio-Repository
37. Adjunctive therapy with LVADs for Recovery
38. Trials in Non-Ischemic Heart Failure
39. Enhancing Stem Cell Homing for Tissue Repair
40. Stroke: Pre-Clinical and Clinical Trial Data