(PDF) Bioinformatics and Drug Discovery 3rd Edition by Richard S. Larson

This is the PDF eBook version for Bioinformatics and Drug Discovery 3rd Edition by Richard S. Larson, Tudor I. Oprea

Table of Contents

1. Cell Perturbation Screens for Target Identification by RNAi

Kubilay Demir and Michael Boutros

2. Using Functional Genomics to Identify Drug Targets: a Dupuytren’s Disease Example

Mirela Sedic, Sandra Kraljevic Pavelic, Karlo Hock

3. Functional Characterization of Human Genes from Exon Expression and RNA Interference Results
Dorothea Emig, Hagen Blankenburg, Fidel Ramírez, and Mario Albrecht

4. Barcode Sequencing for Understanding Drug-gene Interactions

Andrew M. Smith, Tanja Durbic, Saranya Kittanakom, Guri Giaever, Corey Nislow

5. High-Throughput Sequencing of the Methylome Using Two-Base Encoding

Christina A. Bormann Chung

6. Applications and Limitations of In Silico Models In Drug Discovery

Ahmet Secan, Sean Ekins, and Sandhya Kortagere

7. Compound Collection Preparation for Virtual Screening
Cristian G. Bologa and Tudor I. Oprea

8. Mapping Between Databases of Compounds and Protein Targest

Sorel Muresan, Markus Sitzmann, and Christopher Southan

9. Predictive Cheminformatics in Drug Discovery: Statistical Modeling for Analysis of Micro-Array and Gene Expression Data

N. Sukumar, Michael P. Krein, Mark J. Embrechts

10. Advances in Nuclear Magnetic Resonance for Drug Discovery

Laurel O. Sillerud, and Richard S. Larson
11. Human ABC Transporter ABCG2 in Cancer Chemotherapy: Drug Molecular Design to Circumvent Multidrug Resistance

Toshihisa Ishikawa, Hikaru Saito, Hiroyuki Hirano, Yutaka Inoue, Yoji Ikegami

12. Protein Interactions: Mapping Interactome Networks to Support Drug Target Discovery and Selection

Javier De Las Rivas and Carlos Prieto

13. Linking Variants from Genome-Wide Association Analysis to Function via Transcriptional Network Analysis
Benjamin J. Keller, Sebastian Martini, Viji Nair

14. Models of Excitation-Contraction Coupling in Cardiac Ventricular Myocytes

M. Saleet Jafri

15. Integration of Multiple Ubiquitin Signals in Proteasome Regulation

Marta Isasa, Alice Zuin and Bernat Crosas

4. Barcode Sequencing for Understanding Drug-gene Interactions

Andrew M. Smith, Tanja Durbic, Saranya Kittanakom, Guri Giaever, Corey Nislow

5. High-Throughput Sequencing of the Methylome Using Two-Base Encoding

Christina A. Bormann Chung

6. Applications and Limitations of In Silico Models In Drug Discovery

Ahmet Secan, Sean Ekins, and Sandhya Kortagere

7. Compound Collection Preparation for Virtual Screening
Cristian G. Bologa and Tudor I. Oprea

8. Mapping Between Databases of Compounds and Protein Targest

Sorel Muresan, Markus Sitzmann, and Christopher Southan

9. Predictive Cheminformatics in Drug Discovery: Statistical Modeling for Analysis of Micro-Array and Gene Expression Data

N. Sukumar, Michael P. Krein, Mark J. Embrechts

10. Advances in Nuclear Magnetic Resonance for Drug Discovery

Laurel O. Sillerud, and Richard S. Larson
11. Human ABC Transporter ABCG2 in Cancer Chemotherapy: Drug Molecular Design to Circumvent Multidrug Resistance

Toshihisa Ishikawa, Hikaru Saito, Hiroyuki Hirano, Yutaka Inoue, Yoji Ikegami

12. Protein Interactions: Mapping Interactome Networks to Support Drug Target Discovery and Selection

Javier De Las Rivas and Carlos Prieto

13. Linking Variants from Genome-Wide Association Analysis to Function via Transcriptional Network Analysis
Benjamin J. Keller, Sebastian Martini, Viji Nair

14. Models of Excitation-Contraction Coupling in Cardiac Ventricular Myocytes

M. Saleet Jafri

15. Integration of Multiple Ubiquitin Signals in Proteasome Regulation

Marta Isasa, Alice Zuin and Bernat Crosas

10. Advances in Nuclear Magnetic Resonance for Drug Discovery

Laurel O. Sillerud, and Richard S. Larson
11. Human ABC Transporter ABCG2 in Cancer Chemotherapy: Drug Molecular Design to Circumvent Multidrug Resistance

Toshihisa Ishikawa, Hikaru Saito, Hiroyuki Hirano, Yutaka Inoue, Yoji Ikegami

12. Protein Interactions: Mapping Interactome Networks to Support Drug Target Discovery and Selection

Javier De Las Rivas and Carlos Prieto

13. Linking Variants from Genome-Wide Association Analysis to Function via Transcriptional Network Analysis
Benjamin J. Keller, Sebastian Martini, Viji Nair

14. Models of Excitation-Contraction Coupling in Cardiac Ventricular Myocytes

M. Saleet Jafri

15. Integration of Multiple Ubiquitin Signals in Proteasome Regulation

Marta Isasa, Alice Zuin and Bernat Crosas

12. Protein Interactions: Mapping Interactome Networks to Support Drug Target Discovery and Selection

Javier De Las Rivas and Carlos Prieto

13. Linking Variants from Genome-Wide Association Analysis to Function via Transcriptional Network Analysis
Benjamin J. Keller, Sebastian Martini, Viji Nair

14. Models of Excitation-Contraction Coupling in Cardiac Ventricular Myocytes

M. Saleet Jafri

15. Integration of Multiple Ubiquitin Signals in Proteasome Regulation

Marta Isasa, Alice Zuin and Bernat Crosas