This is the PDF eBook version for Methods and Biostatistics in Oncology – Understanding Clinical Research as an Applied Tool by Raphael. L.C Araújo
Table of Contents
Preface
Author: Mithat Gönen – chief of biostatistics department of Memorial Sloan-Kettering Cancer Center – NY – USA.
Background of scientific method in oncology
Author: Vinícius Vazquez – Surgical oncologist – Barretos Cancer Hospital, Barretos, São Paulo, Brazil
Writing a hypothesis for a oncology study
Author: Felipe Fregni, Harvard Medical School
Type of variables and distributions
Author: Gregory Pond, MacMaster, Hamilton, ON, Canada
Testing measures of association
Author: To be defined
Sample size calculation for oncology trials
Author: Ulrich Güller, Kantonsspital St. Gallen, 9007, St Gallen, Switzerland.
Uni and multivariate analysis (understanding of regressions) in cancer research
Author: Marc Buyse, EORTC
Survival analyses in cancer trials
Author: Daniel Sargent, Mayo Clinic
The role of transversal and cohort studies in oncology
Author: To be defined
Design of retrospective and case-control studies in oncology
Author: To be defined
Minimizing differences by randomization
Author: To be defined
How to design phase I trials in oncology
Author: Lillian Siu, Princess Margert Hospital, Toronto, ON, Canada ou Carlos Gil, INCA
The many different designs of phase II oncology trials
Author: Gilberto de Castro e Paulo Hoff?
Superiority and non-inferiority phase III oncology trials
Authors: Everardo Saad, (affiliation TBD)
Phase IV oncology trials
Author:
Analysis of graphs in clinical cancer research
Author: Raphael Araujo – Upper GI and HPB Surgery department; Barretos Cancer Hospital, Barretos, SP, Brazil
Identifying biases in clinical cancer research
Author: Rachel Riechelmann, Instituto do Cancer do Estado de Sao Paulo, Universidade de São Paulo
Ethics in clinical cancer research
Author: Rodrigo Guidalini
Cost-effectiveness studies in oncology
Author: Ian Tannock, Princess Margert Hospital, Toronto, ON, Canada
How to undertake outcomes research in oncology
Author: Christopher Booth, NCI Canada, Kingston, ON
Systematic review and meta-analysis of oncology studies
Author: André Sasse
Meta-research in oncology
Author: Everardo Saad
Analysis of quality of life and patient-reported outcomes in oncology
Author: Janette Vardy, University of Sidney, Australia
Exercises
Commented answers
Glossary