(PDF) Understanding Pathophysiology, Canadian Edition by Huether

This is the PDF eBook version for Understanding Pathophysiology, Canadian Edition by Sue E. Huether, Kelly Power-Kean, Mohamed El-Hussein, Kathryn McCance, Stephanie Zettel

Table of Contents

Preface
Organization and Content
Features to Promote Learning
Art Program
Teaching/Learning Package
Acknowledgments
Introduction to Pathophysiology
Part One Basic Concepts of Pathophysiology
Unit 1 The Cell
1 Cellular Biology
Prokaryotes and Eukaryotes
Cellular Functions
Structure and Function of Cellular Components
Cell-to-Cell Adhesions
Cellular Communication and Signal Transduction
Cellular Metabolism
Membrane Transport: Cellular Intake and Output
Cellular Reproduction: The Cell Cycle
Tissues
Did You Understand?
Key Terms
References
2 Genes and Genetic Diseases
DNA, RNA, and Proteins: Heredity at the Molecular Level
Chromosomes
Elements of Formal Genetics
Transmission of Genetic Diseases
Linkage Analysis and Gene Mapping
Multifactorial Inheritance
Did You Understand?
Key Terms
References
3 Epigenetics and Disease
Epigenetic Mechanisms
Epigenetics and Human Development
Genomic Imprinting
Inheritance of Epigenetic States
Epigenetics and Cancer
Future Directions
Did You Understand?
Key Terms
References
4 Altered Cellular and Tissue Biology
Cellular Adaptation
Cellular Injury
Manifestations of Cellular Injury: Accumulations
Cellular Death
Aging and Altered Cellular and Tissue Biology
Somatic Death
Did You Understand?
Key Terms
References
5 Fluids and Electrolytes, Acids and Bases
Distribution of Body Fluids and Electrolytes
Alterations in Water Movement
Sodium, Chloride, and Water Balance
Alterations in Sodium, Chloride, and Water Balance
Alterations in Potassium and Other Electrolytes
Acid-Base Balance
Pediatric Considerations
Geriatric Considerations
Did You Understand?
Key Terms
References
Unit 2 Mechanisms of Self-Defence
6 Innate Immunity
Human Defence Mechanisms
Acute and Chronic Inflammation
Wound Healing
Pediatric Considerations
Geriatric Considerations
Did You Understand?
Key Terms
References
7 Adaptive Immunity
Third Line of Defence: Adaptive Immunity
Antigens and Immunogens
Antibodies
Immune Response: Collaboration of B Cells and T Cells
Cell-Mediated Immunity
Pediatric Considerations
Geriatric Considerations
Did You Understand?
Key Terms
References
8 Infection and Defects in Mechanisms of Defence
Infection
Deficiencies in Immunity
Hypersensitivity: Allergy, Autoimmunity, and Alloimmunity
Did You Understand?
Key Terms
References
9 Stress and Disease
Historical Background and General Concepts
The Stress Response
Stress, Personality, Coping, and Illness
Geriatric Considerations
Did You Understand?
Key Terms
References
Unit 3 Cellular Proliferation: Cancer
10 Biology of Cancer
Cancer Terminology and Characteristics
The Biology of Cancer Cells
Clinical Manifestations of Cancer
Diagnosis, Characterization, and Treatment of Cancer
Did You Understand?
Key Terms
References
11 Cancer Epidemiology
Genetics, Epigenetics, and Tissue
Incidence and Mortality Trends
In Utero and Early Life Conditions
Environmental and Lifestyle Factors
Did You Understand?
Key Terms
References
12 Cancer in Children and Adolescents
Incidence, Etiology, and Types of Childhood Cancer
Prognosis
Did You Understand?
Key Terms
References
Part Two Body Systems and Diseases
Unit 4 The Neurological System
13 Structure and Function of the Neurological System
Overview and Organization of the Nervous System
Cells of the Nervous System
The Nerve Impulse
The Central Nervous System
The Peripheral Nervous System
The Autonomic Nervous System
Geriatric Considerations
Did You Understand?
Key Terms
References
14 Pain, Temperature, Sleep, and Sensory Function
Pain
Temperature Regulation
Sleep
The Special Senses
Somatosensory Function
Geriatric Considerations
Geriatric Considerations
Geriatric Considerations
Did You Understand?
Key Terms
References
15 Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
Alterations in Cognitive Systems
Alterations in Cerebral Hemodynamics
Alterations in Neuromotor Function
Alterations in Complex Motor Performance
Extrapyramidal Motor Syndromes
Did You Understand?
Key Terms
References
16 Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
Central Nervous System Disorders
Peripheral Nervous System and Neuromuscular Junction Disorders
Tumours of the Central Nervous System
Did You Understand?
Key Terms
References
17 Alterations of Neurological Function in Children
Development of the Nervous System in Children
References
Structural Malformations
Alterations in Function: Encephalopathies
Cerebrovascular Disease in Children
Childhood Tumours
Did You Understand?
Key Terms
References
Unit 5 The Endocrine System
18 Mechanisms of Hormonal Regulation
Mechanisms of Hormonal Regulation
Structure and Function of the Endocrine Glands
Geriatric Considerations
Did You Understand?
Key Terms
References
19 Alterations of Hormonal Regulation
Mechanisms of Hormonal Alterations
Alterations of the Hypothalamic-Pituitary System
Alterations of Thyroid Function
Alterations of Parathyroid Function
Dysfunction of the Endocrine Pancreas: Diabetes Mellitus
Alterations of Adrenal Function
Did You Understand?
Key Terms
References
Unit 6 The Hematological System
20 Structure and Function of the Hematological System
Components of the Hematological System
Development of Blood Cells
Mechanisms of Hemostasis
Pediatric Considerations
Geriatric Considerations
Did You Understand?
Key Terms
References
21 Alterations of Hematological Function
Alterations of Erythrocyte Function
Myeloproliferative Red Blood Cell Disorders
Alterations of Leukocyte Function
Alterations of Lymphoid Function
Alterations of Splenic Function
Hemorrhagic Disorders and Alterations of Platelets and Coagulation
Did You Understand?
Key Terms
References
22 Alterations of Hematological Function in Children
Disorders of Erythrocytes
Disorders of Coagulation and Platelets
Neoplastic Disorders
Did You Understand?
Key Terms
References
Unit 7 The Cardiovascular and Lymphatic Systems
23 Structure and Function of the Cardiovascular and Lymphatic Systems
The Circulatory System
The Heart
The Systemic Circulation
The Lymphatic System
Did You Understand?
Key Terms
References
24 Alterations of Cardiovascular Function
Diseases of the Veins
Diseases of the Arteries
Disorders of the Heart Wall
Manifestations of Heart Disease
Shock
Did You Understand?
Key Terms
References
25 Alterations of Cardiovascular Function in Children
Congenital Heart Disease
Acquired Cardiovascular Disorders
Did You Understand?
Key Terms
References
Unit 8 The Pulmonary System
26 Structure and Function of the Pulmonary System
Structures of the Pulmonary System
Function of the Pulmonary System
Geriatric Considerations
Did You Understand?
Key Terms
References
27 Alterations of Pulmonary Function
Clinical Manifestations of Pulmonary Alterations
Disorders of the Chest Wall and Pleura
Pulmonary Disorders
Did You Understand?
Key Terms
References
28 Alterations of Pulmonary Function in Children
Disorders of the Upper Airways
Disorders of the Lower Airways
Sudden Unexpected Infant Death
Did You Understand?
Key Terms
References
Unit 9 The Renal and Urological Systems
29 Structure and Function of the Renal and Urological Systems
Structures of the Renal System
Renal Blood Flow
Kidney Function
Tests of Renal Function
Pediatric Considerations
Geriatric Considerations
Did You Understand?
Key Terms
References
30 Alterations of Renal and Urinary Tract Function
Urinary Tract Obstruction
Urinary Tract Infection
Glomerular Disorders
Acute Kidney Injury
Chronic Kidney Disease
Did You Understand?
Key Terms
References
31 Alterations of Renal and Urinary Tract Function in Children
Structural Abnormalities
Glomerular Disorders
Nephroblastoma
Bladder Disorders
Urinary Incontinence
Did You Understand?
Key Terms
References
Unit 10 The Reproductive Systems
32 Structure and Function of the Reproductive Systems
Development of the Reproductive Systems
The Female Reproductive System
Structure and Function of the Breast
The Male Reproductive System
Aging and Reproductive Function
Did You Understand?
Key Terms
References
33 Alterations of the Female Reproductive System
Abnormalities of the Female Reproductive Tract
Alterations of Sexual Maturation
Disorders of the Female Reproductive System
Disorders of the Female Breast
Did You Understand?
Key Terms
References
34 Alterations of the Male Reproductive System
Alterations of Sexual Maturation
Disorders of the Male Reproductive System
References
Disorders of the Male Breast
Sexually Transmitted Infections
Did You Understand?
Key Terms
References
Unit 11 The Digestive System
35 Structure and Function of the Digestive System
The Gastro-Intestinal Tract
Accessory Organs of Digestion
Geriatric Considerations
Did You Understand?
Key Terms
References
36 Alterations of Digestive Function
Disorders of the Gastro-Intestinal Tract
Disorders of the Accessory Organs of Digestion
Cancer of the Digestive System
Did You Understand?
Key Terms
References
37 Alterations of Digestive Function in Children
Disorders of the Gastro-Intestinal Tract
Disorders of the Liver
Gastro-Intestinal Malignancies in Children
Did You Understand?
Key Terms
References
Unit 12 The Musculo-skeletal and Integumentary Systems
38 Structure and Function of the Musculo-skeletal System
Structure and Function of Bones
Structure and Function of Joints
Structure and Function of Skeletal Muscles
Aging and the Musculo-skeletal System
Did You Understand?
Key Terms
References
39 Alterations of Musculo-skeletal Function
Musculo-skeletal Injuries
Disorders of Bones
Disorders of Joints
Disorders of Skeletal Muscle
Musculo-skeletal Tumours
Did You Understand?
Key Terms
References
40 Alterations of Musculo-skeletal Function in Children
Congenital Defects
Bone Infection
Juvenile Idiopathic Arthritis
Osteochondroses
Scoliosis
Muscular Dystrophy
Musculo-skeletal Tumours
Nonaccidental Trauma
Did You Understand?
Key Terms
References
41 Structure, Function, and Disorders of the Integument
Structure and Function of the Skin
Disorders of the Skin
Disorders of the Hair
Disorders of the Nail
Geriatric Considerations
Did You Understand?
Key Terms
References
42 Alterations of the Integument in Children
Acne Vulgaris
Dermatitis
Infections of the Skin
Insect Bites and Parasites
Cutaneous Hemangiomas and Vascular Malformations
Other Skin Disorders
Did You Understand?
Key Terms
References
Index
Prefixes and Suffixes Used in Medical Terminology
Word Roots Commonly Used in Medical Terminology