(PDF) Translational Cardiometabolic Genomic Medicine by Annabelle Rodriguez-Oquendo

This is the PDF eBook version for Translational Cardiometabolic Genomic Medicine by Annabelle Rodriguez-Oquendo

Table of Contents

1. Overview of human genome and currently commercially available tests for genetic testing, especially related to cardiometabolic diseases.
2. Overview of genome wide association studies.
3. Overview of publicly available datasets related to genomic medicine that will become important resources for scientists (such as ENCODE). An emphasis will be placed on how scientists can navigate these sites.
4. Overview of genome editing in animal models and cell lines.
5. Overview of experimental approaches such as CHIA-PET to better understand chromosomal structure and long range chromatin interactions.
6. Overview of transcriptome biology, including microRNA biology and lipid metabolism.
7. Genomic medicine and lipid metabolism: LDL targets.
8. Genomic medicine and lipid metabolism: HDL targets.
9. Genomic medicine and diabetes.
10. Genomic medicine and hypertension.
11. Genomic medicine and vascular dementia (including Alzheimers and stroke).
12. Summary of the translational aspects of the basic science of the human genome and its application to the future of medicine.