This is the PDF eBook version for Textbook of Drug Design and Discovery 5th Edition by Kristian Stromgaard, Povl Krogsgaard-Larsen, Ulf Madsen
Table of Contents
Introduction to Drug Design and Discovery
Ulf Madsen and Povl Krogsgaard-Larsen
Molecular Recognition
Thomas Balle and Tommy Liljefors
Ligand-Based Drug Design
Erica S. Burnell, David E. Jane, and Robert J. Thatcher
Biostructure-Based Drug Design
Flemming Steen Jørgensen and Jette Sandholm Kastrup
Drug-Like Properties and Decision Making in Medicinal Chemistry
Jan Kehler, Lars Kyhn Rasmussen, and Morten Jørgensen
Chemical Biology
Louise Albertsen and Kristian Strømgaard
Natural Products in Drug Discovery
Guy T. Carter
In Vivo Imaging in Drug Discovery
Jesper L. Kristensen and Matthias M. Herth
Peptide and Protein Drug Design
Jesper Lau and Søren Østergaard
Prodrugs in Drug Design and Development
Jarkko Rautio and Krista Laine
Enzyme Inhibitors: Biostructure- and Mechanism-Based Design
Robert A. Copeland and P. Ann Boriack-Sjodin
Receptors: Structure, Function, and Pharmacology
Hans Bräuner-Osborne
Ion Channels: Structure and Function
Søren-Peter Olesen, Bo Hjorth Bentzen, and Daniel B. Timmermann
Neurotransmitter Transporters: Structure, Function, and Drug Binding
Claus J. Løland and Ulrik Gether
GABA and Glutamic Acid Receptor and Transporter Ligands
Bente Frølund and Lennart Bunch
Acetylcholine
Anders A. Jensen
Histamine Receptors
Iwan de Esch, Henk Timmerman, and Rob Leurs
Dopamine and Serotonin
Benny Bang-Andersen, Lena Tagmose, and Klaus P. Bøgesø
Opioid and Cannabinoid Receptors
Rasmus P. Clausen and Harald S. Hansen
Neglected Diseases
Søren B. Christensen and Ib C. Bygbjerg
Anticancer Agents
Fredrik Björkling, José Moreira, and Jan Stenvang
Targeting Receptor Tyrosine Kinases
Bo Falck Hansen and Steen Gammeltoft
Antibiotics
Smitha Rao C.V., Piet Herdewijn, and Anastassios Economou