(PDF) Structural Virology by Mavis Agbandje McKenna, Robert McKenna

This is the PDF eBook version for Structural Virology by Mavis Agbandje-McKenna, Robert McKenna, Colin Parrish, Roderick E Hubbard

Table of Contents

Introduction: Principles of Virus Structure;Section 1 Methodologies for Structural Analysis of Viruses; Production and Purification of Viruses for Structural Studies; Microscopic (Confocal) Analysis of Viral Entry and Infection; Cryo-electron Microscopy of Virus Infection – Tomography and Asymmetric Structure Determination; Cryo-electron Microscopy of Viruses – 3D of Virus Capsids; X-ray Crystallography of Virus Capsids; Structural Studies of Viral Proteins; Probing Viral Capsid Structures in Solution; Section 2 Structure to Function Correlation for Viruses; Evolution of Viral Capsid Structures – the Three Domains of Life; Mechanisms of Virus Capsid Assembly; Mechanisms of Genome Packaging; Attachment and Viral entry – Receptor Recognition in Viral Pathogenesis; Attachment and Entry – Viral Cell Fusion; Virus Antibody Recognition; Section 3 Therapeutic Strategies Based on Viral Structures; Development of anti-HIV drugs; Design of Influenza Vaccines and Antiviral Agents; Engineering Viral Capsids as Nano Tools; Viral Vectors for Gene Delivery;