This is the PDF eBook version for Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease by Mark K. Friedberg, Andrew N. Redington
Table of Contents
Introduction.- Embryological origins: How does the RV form?.- The fetal RV: systemic powerhouse or prone to fail?.- Metabolism and bioenergetics in the hypertrophied RV: what is different from the LV?.- Why does the RV myocardium fail?.- Does the RV really contract differently from the LV?.- How does the pressure loaded RV adapt and why does it fail? Macro and molecular perspectives.- Novel mechanisms of lung injury and repair in PAH: does success in the lab translate to hope for our patients?.- Right-left ventricular interactions in PAH.- From M-mode to 3D echo:-what should we use to assess RV function?.- What does MRI offer beyond volumes?.- Why is the RV different in TOF and in ASD?.- RV dyssynchrony and cardiac resynchronization therapy: New insights into mechanisms and pathophysiology.- The single right ventricle in the Fontan circulation: How does it work and why does it fail?.- Transcatheter pulmonary valve replacement: When should we pull the trigger? What do we hope to achieve?.- What should the echocardiographer tell me to plan tricuspid valve repair?.- Investigating the RV: What is the path going forward?.- Ventricular-vascular coupling in PAH: An engineer’s perspective is relevant to the clinician.- The RV in cardiac transplantation-How do we know if it’s going to cope and what do we do when it doesn’t?.- Does the RV really contract differently from the LV?.- How can computer models contribute to the clinician’s assessment of ventricular-ventricular interactions, ventricular-vascular interactions and RV failure?.- Can the RV support the failing LV.- Ebstein anomaly: Does echocardiographic assessment determine surgical repair?.- Arrhythmogenic right ventricular cardiomyopathy: Why does it happen and how do we make the diagnosis?.- Can surgeons preserve RV function in hypoplastic left heart syndrome?.- The RV in ccTGA: Why does it fail? Can we prevent it?.- Drugs?.- Assist devices.- News on the horizon.