This is the PDF eBook version for Principles of Bone Biology 2 VOL Set 3rd Edition by John P. Bilezikian, Lawrence G. Raisz, T. John Martin
Table of Contents
Part I Basic Principles A. Cell Biology Chapter 1: Structure, Modeling and Remodeling of Bone / The Size and Shape of Bone as a Site of Metabolic Bone Activity Chapter 2: Biomechanics of Bone Chapter 3: Embryonic Development of Bone and the Molecular Regulation of Intramembranous and Endochondral Bone Formation Chapter 4:Mesenchymal Stem Cells & Osteoblast Lineage Chapter 5: Transcriptional Control of Osteoblast Differentiation and Function Chapter 6: Wnt Signaling and Bone Chapter 7: Sclerostin and Bone Chapter 8: The Osteocyte Chapter 9: Cells of Bone: Osteoplast Generation Chapter 10: Osteoclast Function: Biology and Mechanisms Chapter 11: RANK Signaling Chapter12: Regulating Bone Resorption Chapter 13: Apoptosis in Bone Cells Chapter 14: Skeletal Gene Expression in Nuclear Microenvironments B. Biochemistry Chapter 15: Type I Collagen: Structure, Synthesis, and Regulation Chapter 16: Collagen Crosslinking & Metabolism Chapter 17: Bone Matrix Proteoglycans & Glycoproteins Chapter 18: Osteopontin Chapter 19: Bone Proteinases Chapter 20: Integrins and Other Cell Surface Attachment Molecules of Bone Cells Chapter 21: Intercellular Junctions and Cell-Cell Communication in the Skeletal System C. Bone Remodeling and Mineral Homeostasis Chapter 22: Histomorphometric Analysis of Bone Remodeling Chapter 23: Phosphorus Homeostasis & Related Disorders Chapter 24: Magnesium Homeostasis Chapter 25: Metals in Bone: Aluminum, Boron, Cadmium, Chromium, Lead, Silicon, & Stro Chapter 26: Biology of the Extracellular Ca2 -Sensing Receptor D. The Hormones of Bone Chapter 27: Receptors for Parathyroid Hormone (PTH) and PTH-Related Protein Chapter 28: Parathyroid Hormone – Molecular Biology Chapter 29: Parathyroid Hormone-Receptor Interactions Chapter 30: Actions of Parathyroid Hormone on the Vasculature and Cardiovascular System Chapter 31: The Vascular and Cardiovascular Actions of PTH Chapter 32: PTH and PTHrP Actions on Kidney and Bone Chapter 33: Physiological Actions of Parathyroid Hormone and PTH-Related Protein Chapter 34: Vascular, Cardiovascular and Neurological Actions of Parathyroid-Related Protein Chapter 35: Vitamin D Nuclear Receptor (VDR) and Plasma Vitamin D-Binding Protein (DBP) Structures and Ligand Shape Preferences for Genomic and Rapid Biological Responses Chapter 36: Vitamin D Gene Regulation Chapter 37: Photobiology and Non-Calcemic Actions of Vitamin D Chapter 38: Calcitonin Structure and Molecular Biology of the Calcitonin Receptor / Calcitonin Gene Family and Receptors: Structure, Molecular Biology, and Effects Chapter 39: Amylin and Calcitonin Gene-Related Peptide E. Other Systemic Hormones That Influence Bone Metabolism Chapter 40: Estrogens & Progestins Chapter 41: The Pharmacology of Selective Estrogen Receptor Modulators Chapter 42: Mechanisms of Estrogen Action in Bone Chapter 43: Thyroid Hormone & Bone Chapter 44: Clinical and Basic Aspects of Glucocorticoid Action in Bone Chapter 45: Effects of Diabetetes & Insulin on Bone Physiology Chapter 46: Androgens:Receptor Expression and Steroid Action in Bone Chapter 47: Kinins & Neuro-Osteogenic Factors Chapter 48: Regulation of Bone Remodeling by Central and Peripheral Nervous Signals Patricia Ducy F. Local Regulators Chapter 49: Insulin-like Growth Factors and the IGF Binding Proteins: Implications for Bone Biology Chapter 50: Platelet-Derived Growth Factor & the Skeleton Chapter 51: Fibroblast Growth Factor (FGF) and FGF Receptor Families in Bone Chapter 52: Vascular Endothelial Growth Factor and Osteogenic-Angiogenic Coupling Chapter 53: Transforming Growth Factor-â Chapter 54: Bone Morphogenetic Proteins and the Skeleton Chapter 55: Bone Morphogenetic Protein Receptors & Actions Chapter 56: Colony-Stimulating Factor-1 Chapter 57: Local Regulators of Bone: IL-1, TNF, Lymphotoxin, Interferon-?, IL-8, IL-10, IL-4, the LIF/IL-6 Family, and Additional Cytokines Chapter 58: Prostaglandins & Bone Metabolism Carol Pilbeam Part II Molecular Mechanisms of Metabolic Bone Disease Chapter 59: Skeletal Effects of Nitric Oxide: Novel Agent for Osteoporosis Chapter 60: Molecular Basis of PTH Overexpression Chapter 61: Familial Benign Hypocalciuric Hypercalcemia and Neonatal Primary Hyperparathyroidism Chapter 62: Multiple Endocrine Neoplasia Type I Chapter 63: Parathyroid Hormone-Related Peptide and Other Systemic Factors in Skeletal Manifestations of Malignancy Chapter 64: Local Factors in Skeletal Malignancy Chapter 65: Genetic Regulation of the Parathyroid Gland Development Chapter 66: Jansen’s Metaphyseal Chondrodysplasia & Blomstrand’s Lethal Chondrodysplasia: Two Genetic Disorders Caused by PTH/PTHrP Receptor Mutations Chapter 67: Diseases Resulting from Defects in the G Protein Gs Chapter 68: Renal Osteodystrophy – Pathogenic Mechanisms and Therapeutic Options Chapter 69: Osteogenesis Imperfecta Chapter 70: Hereditary Deficiencies in Vitamin D Action Chapter 71: Oncogenic Osteomalacia Chapter 72: Osteopetrosis Chapter 73: Hypophosphatasia: Nature’s Window on Alkaline Phosphatase Function in Humans Chapter 74: Paget’s Disease of Bone Chapter 75: Genetic Determinants of Bone Mass and Osteoporotic Fracture Chapter 76: Pathophysiology of Osteoporosis Chapter 77: Evaluation of Risk for Osteoporosis Fracture Part III Pharmacological Mechanisms of Therapeutics Chapter 78: Parathyroid Hormone Chapter 79: Calcium Chapter 80: Drugs Acting on the Calcium Receptor Calcimimetics and Calcilytics Chapter 81: Bisphosphonates: Mechanisms of Action Chapter 82: The Pharmacology of Estrogens in Osteoporosis Chapter 83: Vitamin D & Analogs Chapter 84: Estrogen Effects on Bone in the Male Skeleton Chapter 85: Mechanisms of Exercise Effects on Bone Quantity and Quality
Part IV Methods in Bone Research Chapter 86: Application of Transgenic Mice to Problems of Skeletal Bone Chapter 87: Biochemical Markers of Bone Metabolism Chapter 88: Methods and Clinical Issues in Bone Densitometry Chapter 89: Controversial Issues in Bone Densitometry Chapter 90: Macro and Micro Imaging of Bone Architecture