(PDF) Molecular and Cellular Mechanisms of Antibody Activity by Nimmerjahn

This is the PDF eBook version for Molecular and Cellular Mechanisms of Antibody Activity by Falk Nimmerjahn

Table of Contents

IgM and IgD in infection and inflammatory diseases.- Immunoglobulin A – molecular mechanisms of function and role in immune defense.- Crystal structures of human IgG Fc-fragments and their complexes with Fc Receptors.- The role of IgG in immune responses.- Molecular and cellular pathways involved in the anti-inflammatory activity of IgG.- Example of the Pathogenic Potential of Two Sets of Autoantibodies: Anti-RBC and IgG3 RF Cryoglobulins.- Cross-talk between antibodies, IgG Fc receptors and the complement system.- Regulation of immunological responses by the neonatal Fc receptor for IgG, FcRn.- Antibody mediated regulation of humoral immunity.- Engineered antibody derivatives in preclinical and clinical development.