(PDF) Heat Shock Proteins and the Brain 1st Edition by Alexzander A.A. Asea

This is the PDF eBook version for Heat Shock Proteins and the Brain – Implications for Neurodegenerative Diseases and Neuroprotection 1st Edition by Alexzander A.A. Asea, Ian R. Brown

Table of Contents

Part I: Heat Shock Proteins and Neurodegenerative Diseases: 1. Chaperones and Polyglutamine Expansion Disorders, Martin L. Duennwald; 2. Heat Shock Proteins, Unfolded Protein Response Chaperones and Alzheimer’s Disease, Jordi Magrane and Henry W. Querfurth; 3. Cellular and Molecular Mechanisms Underlying Parkinson’s Disease: The Role of Molecular Chaperones, Pamela J. McLean; 4. Heat Shock Proteins as Therapeutic Targets in Amyotrophic Lateral Sclerosis, Bernadett Kalmar and Linda Greensmith; 5. The Role of Chaperones and Co-Chaperones in Retinal Degenerative Diseases, Maria Kosmaoglou, Tatiana V. Novoselova and Michael E. Cheetham; 6. Neuroprotective Features of Hsp90 Inhibitors Exhibiting Anti-Inflammatory Actions: Implications for Multiple Sclerosis, Douglas L. Feinstein, Alessandra Spagnolo and Cinzia Dello-Russo; 7. Role of HspB1 and HspB8 in Hereditary Peripheral Neuropathies: Beyond the Chaperone Function, Serena Carra and Jacques Landry; Part II: Heat Shock Proteins and Neuroprotection: 8. Heat Shock Proteins Hsp70 and Hsp27 and Neural Cellular Protection, Tracy S. Voegeli, Amanda J. Wintink and R. William Currie; 9. Molecular Chaperones and Protection in Animal and Cellular Models of Ischemic Stroke, Yi-Bing Ouyang, Lijun Xu and Rona G. Giffard; 10. Strategies for Conferring Neuroprotection and Countering the High Threshold for Induction of the Stress Response in Motor Neurons, Heather D. Durham; 11. Use of Viral Gene Delivery Systems to Investigate Neuroprotective Roles of Hsp70 and Hsp40 Proteins, Joanna Howarth, Do-Young Lee and James B. Uney; 12. Heat Shock Proteins at the Synapse: Implications for Functional Protection of the Nervous System, Ian R. Brown; Part III: Extracellular Heat Shock Proteins and the Nervous System: 13. Release of Heat Shock Proteins and their Effects when in the Extracellular Space in the Nervous System, Michael Tytell, Mac B. Robinson and Carolanne E. Milligan; 14. Silencing of Metastasis-Associated Gene 1 (mta1) Stimulates Hsp70 Cellular Release and Neurite Extension in Neuroblastoma Cells, Preethi Rao and Alexzander Asea; 15. Extracellular Chaperones and Amyloids, Mark R. Wilson, Justin J. Yerbury and Stephen Poon; Part IV: Aging, Control of Life Span and Expression of Heat Shock Proteins: 16. Neural Expression of Small Heat Shock Proteins Influences Longevity and Resistance to Oxidative Stress, Robert M. Tanguay and Geneviève Morrow; 17. Mechanistic Links Between Aging and Aggregation-Mediated Proteotoxicity: Role of HSF-1 and DAF-16, Ehud Cohen and Andrew Dillin; 18. Protein Quality Control and Heat Shock Gene Expression in the Nervous System, Stuart K. Calderwood; 19. Serum HSP70 Level as a Biomarker of Exceptional Longevity, Dellara F. Terry and Alexzander Asea; Index