(PDF) Genome Editing – The Next Step in Gene Therapy by Cathomen

This is the PDF eBook version for Genome Editing – The Next Step in Gene Therapy by Toni Cathomen, Matthew Hirsch, Matthew Porteus

Table of Contents

1. Gene Editing: Double-Strand
Break Induced Gene Targeting and Mutagenesis 20 Years Later.- 2. The
Development and Use of Zinc-Finger Nucleases.- 3.The Use and Development of TAL
Effector Nucleases.- 4. Genome Editing for Neuromuscular Diseases.- 5. Phage
Integrases for Genome Editing.- 6. Precise Genome Modification Using Triplex
Forming Oligonucleotides and Peptide Nucleic Acids.- 7. Genome Editing by
Aptamer-Guided Gene Targeting.- 8. Stimulation of AAV Gene Editing via DSB
Repair.- 9. Engineered Nucleases and Trinucleotide Repeat Diseases.- 10. Using
Engineered Nucleases to Create HIV-Resistant Cells.- 11. Strategies to
Determine Off-Target Effects of Engineered Nucleases.