This is the PDF eBook version for Gene and Cell Therapy – Therapeutic Mechanisms and Strategies 4th Edition by Nancy Smyth Templeton

Delivery Systems and Therapeutic Strategies
Lentiviral Vectors: Design and Applications Anais Girard and Els Verhoeyen
Adenovirus-Vector-Mediated Gene Delivery: Barriers and Chemical Vector Modifications Florian Kreppel
Helper-Dependent Adenoviral Vectors for Gene Therapy Nicola Brunetti-Pierri and Philip Ng
Adeno-Associated Virus and AAV Vectors for Gene Delivery Barrie J. Carter
Vaccinia Viral Vectors for Vaccines and Oncolytic Virotherapy Z. Sheng Guo, J. Andrea McCart, and David L. Bartlett
Oncolytic Measles Virus-Based Delivery Systems Pavlos Msaouel and Evanthia Galanis
Alphavirus Vectors in Gene Therapy and Neuroscience Kenneth Lundstrom
Oncolytic Viruses for Treatment of Cancer Akseli Hemminki, Markus Vähä-Koskela, and Vincenzo Cerullo
Baculovirus: A High-Capacity Vector for Versatile Gene Transfer
Kari J. Airenne and Seppo Ylä-Herttuala
Baculovirus as a Gene Delivery Vector for Bone and Cartilage Tissue Engineering Chin-Yu Lin, Chiu-Ling Chen, Li-Yu Sung, Kuei-Chang Li, Chia-Lin Yeh, and Yu-Chen Hu
Bacteria as Gene Therapy Vectors for Cancer William L. Byrne and Mark Tangney
Redox-Responsive Polymer-Based Gene Delivery Systems Yu Zhu, Jing Li, Yan Wang, Devika Soundara Manickam, Yezi You, and David Oupický
Receptor-Targeted Polyplexes for pDNA and siRNA Delivery Linda Beckert, Alexander Philipp, and Ernst Wagner
Dendrimers, Dendrigrafts, and Their Conjugations as Delivery Vectors in Gene Therapy Ampornphan Siriviriyanun and Toyoko Imae
Gene Electrotransfer Shawna A. Shirley, Loree C. Heller, and Richard Heller
Magnetofection: Using Magnetic Particles and Magnetic Force to Enhance and Target Nucleic Acid Delivery Christian Plank, Dialechti Vlaskou, Yolanda Sanchez-Antequera, and Olga Mykhaylyk
New Advances in Cell-Based Drug and Gene Delivery Systems José M. Lanao, Carmen Gutiérrez Millán, and Clara Isabel Colino Gandarillas
Pressurized Transvenous-Retrograde Extremity Perfusion Zheng Fan, William Powers, Joe Kornegay, and Xiao Xiao
Optimization of Nonviral Gene Therapeutics Using Bilamellar Invaginated Vesicles Nancy Smyth Templeton

Other Therapeutic Strategies
Antisense Oligonucleotide–Based Therapeutics C. Frank Bennett, Eric Swayze, Scott Henry, and Richard Geary
Development of RNAi Therapeutics Akin Akinc, Brian R. Bettencourt, and Martin A. Maier
Therapeutic Applications of Morpholino Oligonucleotides David R. Soto-Pantoja, Jeffrey S. Isenberg, and David D. Roberts
Therapeutic Potential of microRNAs Tina Catela Ivkovic and George A. Calin

Gene Expression, Regulation, and Detection; Genome Modifications
Monitoring Gene and Cell Therapies in Living Subjects with Molecular Imaging Technologies John Ronald, Sandip Biswal, and Sanjiv Sam Gambhir
Deliberate Regulation of Therapeutic Transgenes: Recent Advances in System Development and Uses Nuria Vilaboa and Richard Voellmy
Nonviral Genome Modification Strategies for Gene Therapy: Transposon, Integrase, and Nuclease Systems Lauren E. Woodard and Michele P. Calos
Selectable Markers for Gene Therapy Jean-Pierre Gillet, Ryan C. Hunt, Chava Kimchi-Sarfaty, Tal Kafri, Jizhong Zou, Mahendra S. Rao, and Michael M. Gottesman

Gene and Cell Therapies, Disease Targets, Clinical Trials, and Regulatory Issues
Pluripotent Stem Cells and Their Therapeutic Applications Sadaf Amin and Shuibing Chen
Adult Lung Stem Cells Amritha Kidiyoor, Anthony Atala, and Sean V. Murphy
Placenta-Derived Cells and Their Therapeutic Applications De Debashree, Gabriela Kmiecik, Anna Cargnoni, and Ornella Parolini
Directing Pluripotent Human Embryonic Stem Cells toward Lineage-Specific Cell Therapy Derivatives for Regenerative Medicine Xuejun H. Parsons
Surgical and Translational Aspects of Tissue Engineering Peggy Lange, Jonathan M. Fishman, Paolo De Coppi, and Martin A. Birchall
DNA Vaccines Jian Yan and David B. Weiner
Cell and Gene Therapies for Cardiovascular Disease Michael G. Katz, Anthony S. Fargnoli, Richard D. Williams, and Charles R. Bridges
Gene Therapy for Hematopoietic Disorders Elizabeth M. Kang and Harry L. Malech
Update on Preclinical and Clinical Gene Therapy for the Treatment of Cystic Fibrosis Uta Griesenbach and Eric Alton
Gene Therapy for Vision Disorders Deniz Dalkara and José-Alain Sahel
Cell and Gene Therapies for the Treatment of Hearing Disorders Lisa N. Gillespie, Rachael T. Richardson, Andrew K. Wise, and Bryony A. Nayagam
Molecular Therapy for Type 1 and Type 2 Diabetes Susan Leanne Samson, Vijay Yechoor, and Lawrence Chan
Alipogene Tiparvovec: Gene Therapy for Familial Lipoprotein Lipase Deficiency Norman E. Miller
Gene and Cell Therapies for Muscular Dystrophies Sara Benedetti, Giulio Cossu, and Francesco Saverio Tedesco
Gene Therapy Clinical Trials for Muscular Dystrophy Louise R. Rodino-Klapac and Jerry R. Mendell
RNA Interference-Based Gene Therapy Strategies for the Treatment of HIV Infection Lisa J. Scherer, John C. Burnett, and John J. Rossi
Gene Therapy for the Treatment of Cancer: From Laboratory to Bedside Carlos A. Ramos, Barbara Savoldo, and Gianpietro Dotti
Gene Therapy for the Treatment of Lung Cancer Humberto Lara-Guerra and Jack Roth
FANG: bi-shRNAifurin and GMCSF DNA-Augmented Autologous Tumor Cell Vaccine: Clinical Results John Nemunaitis, Donald D. Rao, and Neil Senzer
Cutaneous Cell- and Gene-Based Therapies for Inherited and Acquired Skin Disorders Jean Christopher Chamcheu, Vaqar M. Adhami, Imtiaz A. Siddiqui, and Hasan Mukhtar
Cell Therapy for the Creation of Cartilage and Related Clinical Trials Jonathan Karnes, Ying Zhang, and Ming Pei
Cell Therapies for the Treatment of Inborn Metabolic Errors María José Gómez-Lechón, Laia Tolosa, Eugenia Pareja, and José V. Castell
Cell Therapies for Lung Disease Rebecca Lim, Jean L. Tan, and Euan M. Wallace
Gene Therapy for Neurological Diseases Massimo S. Fiandaca, Shreyas Mahapatra, Suresh de Silva, William J. Bowers, and Howard J. Federoff
Gene Therapy for Alzheimer’s Disease Alan H. Nagahara and Mark H. Tuszynski
Translating Stem Cell Therapy for Alzheimer’s Disease Kazutaka Shinozuka, Paolina Pantcheva, Sandra Acosta, Mibel Pabon, Naoki Tajiri, Yuji Kaneko, and Cesar V. Borlongan
Regulatory Aspects of Gene Therapy Daniel Takefman and Lilia Bi