(PDF) Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies By Abelson

This is the PDF eBook version for Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies By Abelson, John N., Simon, Melvin I.

Table of Contents

Preface
Volumes In Series
Section I: General Methods
Chapter 1. Progress in Antisense Technology: The End of the Beginning
Chapter 2. Basic Principles of Using Antisense Oligonucleotides in Vivo
Chapter 3. Polyethyleneimine-Mediated Transfection to Improve Antisense Activity of 3′ -Capped Phosp
Chapter 4. Design of Antisense and Triplex-Forming Oligonucleotides
Chapter 5. Chimeric Oligodeoxynucleotide Analogs: Chemical Synthesis, Purification, and Molecular an
Chapter 6. Evaluation of Antisense Mechanisms of Action
Chapter 7. Physiology and Molecular Biology Brought to Single-Cell Level
Chapter 8. Antisense Properties of Peptide Nucleic Acid
Chapter 9. Synthesis of Oligonucleotide Conjugates in Anhydrous Dimethyl Sulfoxide
Chapter 10. Gene Switching: Analyzing Broad Range of Mutations Using Steric Block Antisense Oligonuc
Chapter 11. Vesicular Stomatitis Virus as Model System for Studies of Antisense Oligonucleotide Tran
Chapter 12. Purification of Antisense Oligonucleotides
Chapter 13. Boranophosphate Backbone: A Mimic of Phosphodiesters, Phosphorothioates, and Methyl Phos
Chapter 14. Intracellular Distribution of Digoxigenin-Labeled Phosphorothiate Oligonucleotides
Chapter 15. Use of Minimally Modified Antisense Oligonucleotides for Specific Inhibition of Gene Exp
Section II: Methods of Delivery
Chapter 16. Determination of Cellular Internalization of Fluorescent Oligonucleotides
Chapter 17. Intrabody Tissue-Specific Delivery of Antisense Conjugates in Animals: Ligand–Linker A
Chapter 18. Lipid-Based Formulations of Antisense Oligonucleotides for Systemic Delivery Application
Chapter 19. In Vitro Transport and Delivery of Antisense Oligonucleotides
Chapter 20. In Vitro and in Vivo Delivery of Antisense Oligodeoxynucleotides Using Lipofection: Appl
Chapter 21. Preparation and Application of Liposome-Incorporated Oligodeoxynucleotides
Chapter 22. Cell-Specific Optimization of Phosphorothioate Antisense Oligodeoxynucleotide Delivery b
Section III: RNA Studies
Chapter 23. Intracellular Expression and Function of Antisense Catalytic RNAs
Chapter 24. Selective Degradation of Targeted mRNAs Using Partially Modified Oligonucleotides
Chapter 25. Reversible Depletion of Specific RNAs by Antisense Oligodeoxynucleotide-Targeted Degrada
Chapter 26. Inactivation of Gene Expression Using Ribonuclease P and External Guide Sequences
Chapter 27. Disruption of mRNA-RNP Formation and Sorting to Dendritic Synapses by Antisense Oligonuc
Chapter 28. Antisense RNA and DNA in Escherichia coli
Chapter 29. Utilization of Properties of Natural Catalytic RNA to Design and Synthesize Functional R
Chapter 30. Antisense Oligonucleotides and RNAs as Modulators of pre-mRNA Splicing
Chapter 31. Selective RNA Cleavage by Isolated RNase L Acti- vated with 2–5A Antisense Chimeric Ol
Author Index
Subject Index