(eBook) Epigenetic Alterations in Oncogenesis By Adam R. Karpf

This is the PDF eBook version for Epigenetic Alterations in Oncogenesis By Adam R. Karpf

Table of Contents

Frontmatter
1. Epigenetic Marks and Mechanisms
1. DNA Methyltransferases, DNA Damage Repair, and Cancer
2. DNA Hypomethylation and Hemimethylation in Cancer
3. Ten Eleven Translocation Enzymes and 5-Hydroxymethylation in Mammalian Development and Cancer
4. Altered Histone Modifications in Cancer
5. Nucleosome Occupancy and Gene Regulation During Tumorigenesis
2. The Impact of Epigenetic Alterations on Cancer Biology
6. Epigenetic Regulation of miRNAs in Cancer
7. DNA Hypomethylation and Activation of Germline-Specific Genes in Cancer
8. APC and DNA Demethylation in Cell Fate Specification and Intestinal Cancer
9. Epigenetic Changes During Cell Transformation
10. Epigenetic Reprogramming of Mesenchymal Stem Cells
3. Clinical Implications and Analysis Methods
11. Environmental Toxicants, Epigenetics, and Cancer
12. Blood-Derived DNA Methylation Markers of Cancer Risk
13. Epigenetic Therapies in MDS and AML
14. Epigenetic Targeting Therapies to Overcome Chemotherapy Resistance
15. Methods for Cancer Epigenome Analysis
Backmatter