(eBook) Developments in T Cell Based Cancer Immunotherapies by Paolo A. Ascierto

This is the PDF eBook version for Developments in T Cell Based Cancer Immunotherapies by Paolo A. Ascierto, David F. Stroncek, Ena Wang

Table of Contents

.-1 New insight of peptide vaccination in cancer immunotherapy

.-2 The determinants of T cell function for effective anticancer vaccine

.-3 T cell fate in the tumor microenvironment

.-4 T cell receptor avidity and affinity and tumor specific TCR engineer

.-5 Host genetic variation and somatic alteration associated with favorable or compromised T cell function

.-6 Production of Clinical T Cell Therapies

.-7 Clinical success of adoptive cell transfer therapy using tumor infiltrating lymphocytes

.-8 Harnessing stem cell-like memory T cells for adoptive cell transfer therapy of cancer

.-9 T cell blockade- anti-CTLA4 immunotherapy against cancer and Abscopal effect in combination therapy

.-10 T cell modulation- anti-OD-1 antibodies for the treatment of cancer

.-11 T cell based therapies in combination with other procedures

.-12 Chimeric antigen receptor T cells CD19 CAR

.-13 Hematopoietic Stem Cell transplantation as immune therapy of malignancies