(eBook) Antibacterial Drug Discovery to Combat MDR by Iqbal Ahmad

This is the PDF eBook version for Antibacterial Drug Discovery to Combat MDR – Natural Compounds, Nanotechnology and Novel Synthetic Sources by Iqbal Ahmad, Shamim Ahmad, Kendra P. Rumbaugh

Table of Contents

Section A: Problems associated with current antimicrobial therapy
1. Antibacterial drug discovery : perspective insights2. Emergence and spread of multidrug resistance in ocular pathogens3. Problematic groups of MDR bacteria and their resistance mechanisms4. Biofilms in relation to enhanced drug resistance and persistence infection: challenges in chemotherapy5. Environmental MDR a potential threat to human health and antimicrobial therapy6. Impediments to discovery of new antimicrobials with new modes of action7. Developing in vivo infection models with MDR pathogens for evaluating compound efficacy
Section B: New antibiotic drug discovery approaches and progress8. Classical to improved microbial screening approaches for antibacterial drug discovery9. Endophytes: a hidden treasure of novel antimicrobial metabolites10. New molecular drug targets: potential for developing novel antibacterials against MDR bacteria11. Bio-synthetic gene clusters associated with marine sponge and with bacterial dwelling in marine sponges12. Insilico molecular modelling for drug screeningbioinformatics and chemoinformatics: key technologies in the drug discovery process13. Computational Approaches in relation to antibacterial drug discovery14. Efflux pump inhibitors and their role in reversal of drug resistance15. Medicinal plants as reservoir of new structure for anti-infective compounds16. Antibacterial essential oils: Potential application in bacterial disease management.17. Metagenomic approach to explore soil resistome.18. Marinemicrobes as promising source of new leads as antibacterials: Current progress and prospects
Section C:Alternative antibiotic resistance treatment strategy19. Role of pre and probiotics in protection from pathogenic bacteria20. Enhancing antibiotic efficacy through synergistic approach21. Reviving old antibiotics22. Targeted Delivery of antibiotics using polymeric particles to combat TB resistance23. Bacteriophages in pathogenic bacterial control: prospects and limitation.24. Inhibition of Quorum sensing; prospects in disease control25. Pathogenic Biofilm eradication strategies in combating bacterial infection
Section D:Nanomaterials as antibacterial drug: potentials and prospects26. Nanomedicine /Nanoemulsion in increasing drug availability27. Nanoparticle as new emerging antibacterials: potential and limitation28. Antibiofilm and antivirulence action of nanopartciles29. Nanoparticle-based drug delivery systems: promising approaches against bacterial infections30. Green synthesis of metal nanoparticles: characterization and their antibacterial efficacy31. Protein and Peptide Nanoparticles for antibacterial Drug Delivery